The present invention relates to methods of treating an individual with diabetes
mellitus by administering to said individual an effective amount of copper chelators,
hydrazine compounds, and/or substrate analogues. The invention also relates to
methods of treating an individual with diabetes mellitus by lessening fructosamine
odixase activity in said individual. Provided within is disclosure pertaining to
treatment, pharmaceutical compositions, dosage ranges, and uses of fructosamine
oxidase enzyme inhibitors to lessen fructosamine oxidase activity.
