A miniaturized temperature-zone flow reactor, used for thermally controlled biochemical
or molecular-biological processes, especially polymerase chain reaction (PCR) enables
more efficient reactions by providing at least one closed flow path which is divided
into three partial paths (A1 . . . An; B1 . . . Bn and BB1 .
. . BBn-1; C1 . . . Cn) with the reactor having three substrate chips (A;
B; C) which are made of a material having a high heat conductivity, and which have
defined channel sections that are spaced apart relative to each other, and are
connected by a connecting chip (V) made of a poor heat-conductive material. The
substrate chips (A; B; C) are maintained at different temperatures by various means,
including the use of controlling heating elements in contact with the chips.