The yield of active polysaccharides contained in Agaricus blazei, such
as -glucan, can be improved, by decomposing and treating the mycelium or
fruit body of Agaricus blazei or a liquid waste of the culture of the mycelium
with an enzymatic agent principally comprising hemicellulase.
By increasing the concentrations of the active polysaccharides, furthermore,
the
digestion and absorption of the biologically active substance of the present invention
after the incorporation thereof into bodies is prominently elevated, so that the
active substance can exert excellent immune activation effect on cancers and other
adult diseases.