Sulfonyl-Derivatives as novel inhibitors of histone deacetylase

   
   

This invention comprises the novel compounds of formula (I) wherein n, m, t, R.sup.1, R.sup.2, R.sup.3, R.sup.4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine. 1

 
Web www.patentalert.com

< Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease

< Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors

> Characterizing biological stimuli by response curves

> Method for the prevention or treatment of pain, inflammation and inflammation-related disorders with a Cox-2 selective inhibitor in combination with a nitric oxide-donating agent and compositions therewith

~ 00183