The subject invention provides methods for evaluating women in designing appropriate
menopausal and postmenopausal therapies to match the particular needs of the individual.
In one embodiment, the subject invention provides methods for evaluating particular
factors in menopausal and postmenopausal women that are then taken into account
in identifying a therapy program to promote good health and reduce the risk of
any adverse health effects as a result of the therapy, specifically the role of
hormone induced/associated breast cancer. More specifically, the subject invention
includes methods for evaluating menopausal and postmenopausal women to determine
whether hormone replacement therapy is appropriate in this regard, and if so, the
specifics of how that therapy is to be administered. The subject invention, by
incorporating various factors into a comprehensive, function breast hormone profile,
allows for the identification of untreated women with estrogen-related metabolic
abnormalities that may increase the risk of breast cancer. The subject invention
determines specific therapies to correct and/or inhibit the aberrant biosynthetic
pathways, and thus, the risk of cancer.
