Measurement of protective genes in allograft rejection

   
   

The invention relates to methods of evaluating transplant rejection in a host comprising determining a heightened magnitude of gene expression of genes in rejection-associated gene clusters. The disclosed gene clusters include genes that are substantially co-expressed with cytotoxic lymphocyte pro-apoptotic genes, cytoprotective genes and several other cytokine and immune cell genes.

 
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> 68999, a human ubiquitin carboxyl-terminal hydrolase family member and uses therefor

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