This invention relates to methods for reducing the presence of a compound in
an ionically conductive material, e.g., for use in iontophoretic devices, wherein
the presence of the compound interferes with detecting a selected analyte. Removal
of the compound can typically take place either during or after the manufacture
of the ionically conductive material or an assembly comprising this material. Also
disclosed are methods for generating selectively permeable barriers on the reactive
faces of electrodes. Further, this invention relates to hydrogels comprising one
or more biocides, as well as assemblies containing such hydrogels.