The present invention discloses compositions derived from an isolated Bacillus
species, spores, or an extracellular product of Bacillus coagulans comprising
a supernatant or filtrate of a culture of said Bacillus coagulans strain,
suitable for topical application to the skin or mucosal membranes of a mammal,
which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and
combinations thereof. The present invention also discloses methods of treatment
and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus,
and combinations thereof, by topical application of therapeutic compositions which
are comprised, in part, of isolated Bacillus species, spores, or an extracellular
product of Bacillus coagulans comprising a supernatant or filtrate of a
culture of said Bacillus coagulans strain. In addition, the present invention
also discloses compositions, methods of treatment, and therapeutic systems for
inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof,
comprising an extracellular product of Pseudomonas lindbergii comprising
a supernatant or filtrate of a culture of said Pseudomonas lindbergii strain.