The invention is a novel method and precursor for preparing radiolabeled
nucleosides. In particular, the invention is useful for preparing
3'-[.sup.18F]fluorothymidine. The method uses an enol group that is
attached to the 2-position on the pyrimidine ring. The enol group
attenuates thymidines activity so that the thymidine is easily
radiolabeled in short number of steps with good yield.