Indolinone combinatorial libraries and related products and methods for the treatment of disease
   
   

The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.

 
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> Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection

> Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device
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