Assay for beta cell toxic macrolides

   
   

The present invention relates to a method of assessing the propensity of a plant, if consumed, to contribute to the onset and/or progression of diabetes in a mammal and, more particularly, to a method of assessing the propensity of a tuberous vegetable, if consumed, to contribute to the onset and/or progression of diabetes in a mammal. The method of the present invention is useful, inter alia, for identifying mammals at risk of developing diabetes based on dietary intake. The present invention is further directed to methods of assessing the risk status of an individual for development of diabetes. The present invention still further provides methods for the prophylactic and/or therapeutic treatment of diabetes.

 
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> Heterocyclic amide derivatives having glycogen phosphorylase inhibitory activity

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