The invention is drawn to silane copolymers prepared from the reaction of one
or more polyisocyanates with one or more lubricious polymers having at least two
functional groups, which may be the same or different, that are reactive with an
isocyanate functional group and with one or more organo-functional silanes having
at least two functional groups, which may be the same or different, that are reactive
with an isocyanate functional group and at least one functional group reactive
with a silicone rubber substrate. The silane copolymer coatings of the invention
are elastic, lubricious, and resist wet abrasion. They are useful as coatings for
polysiloxane (rubber) and other difficult to coat substrates, especially for medical
devices, such catheters.