The invention provides isolated nucleic acids molecules, designated 57316 or
33338 nucleic acid molecules, which encode ubiquitin carboxyl terminal hydrolase
proteins. The invention also provides antisense nucleic acid molecules, recombinant
expression vectors containing 57316 or 33338 nucleic acid molecules, host cells
into which the expression vectors have been introduced, and non-human transgenic
animals in which a 57316 or 33338 gene has been introduced or disrupted. The invention
still further provides isolated 57316 or 33338 proteins, fusion proteins, antigenic
peptides and anti-57316 or 33338 antibodies. Diagnostic and therapeutic methods
utilizing compositions of the invention are also provided.
