Methods for isolating pancreatic progenitor 1 genes are provided. The pancreatic
progenitor 1 nucleic acid compositions find use in identifying homologous or related
proteins and the DNA sequences encoding such proteins; in producing compositions
that modulate the expression or function of the protein; and in studying associated
physiological pathways. In addition, modulation of the gene activity in vivo is
used for prophylactic and therapeutic purposes, such as identification of cell
type based on expression, and the like.