The invention provides a prophylactic and therapeutic agent of diabetes
mellitus, including a combination of an inhibitor of renal glucose
reabsorption and a hypoglycemic agent. In accordance with the invention,
hyperglycemia after meals, between meals and during fasting can be
ameliorated. More specifically, in accordance with the invention, a
therapeutic effect of diabetes mellitus as never been obtained by the
hypoglycemic agents of the related art can be achieved.
