The present invention provides cystine derivatives, which may be in a free form,
a salt form, a solvate form. The cystine derivatives of the present invention may
be used to suppress activation of inflammatory factors. Accordingly, the present
invention provides: compositions containing the cystine derivatives; a method for
suppressing the activation of inflammatory factors by administering the composition;
a method for preventing, ameliorating and/or therapeutically treating diseases,
skin injuries or disorders involved in the activation of inflammatory factors by
administering the composition; a method for preventing, delaying, ameliorating
and/or therapeutically treating skin change via aging or aesthetically unfavorable
skin change as induced or promoted by inflammatory factors by administering the
composition; and pharmaceutical agents containing the cystine derivatives.