Disclosed are catalytic antibodies and polypeptides capable of degrading
cocaine. Said catalytic antibodies and polypeptides are characterized by the amino
acid sequence of their complementary determining regions and framework regions.
The present invention also discloses a pharmaceutical composition and a method
for decreasing the concentration and a method for decreasing the concentration
of cocaine of a subject. Finally, the invention discloses pharmaceutical compositions
and methods for treating cocaine overdose and addiction in subjects.
