A novel group of aminoglycosides which share some structural features of
currently available aminoglycosides with regard to the backbone, while
also having significant structural differences, is disclosed. The
similarity enables these aminoglycosides to be highly potent and
effective antibiotics, while the significant differences enable these
aminoglycosides to reduce or even block antibiotic resistance. The
aminoglycosides of the present invention are suitable for inhibition of
antrax lethal factor, hence are suitable for use as a cure for anthrax.
