A robotic autosampler provides for automated manipulation of microfluidic
chips having multiple electrospray devices and/or sample inlets for
interface to a mass spectrometer or other detection device. The
autosampler also provides for connection of control voltages to the
electrospray device to facilitate enablement, control and steering of
charged droplets and ions. The autosampler further provides a method of
fluid delivery that may be disposable or reusable. The delivery device
may contain materials for component separation or sample purification.
The delivery device may contain preloaded sample or the sample may be
loaded by the autosampler. A method for automated manipulation of
multiple electrosprays in communication with a detector, includes:
providing a robot autosampler having an electrospray chip;
electrospraying at least one analyte from at least one electrospray
device on the electrospray chip; and manipulating the electrospray chip
in communication with a detector in a manner to detect analyte from the
electrospray.
