Compositions comprising a plurality of yeast cells, wherein said plurality
of yeast cells are characterized by their ability to ameliorate renal failure (e.g.,
improved diuretic effect and/or lowering blood urea nitrogen, proteinuria, and/or
serum creatinine levels) in a subject as a result of having been cultured in the
presence of an alternating electric field having a specific frequency and a specific
field strength. Also included are methods of making and using such compositions.