The present invention provides a transdermal drug delivery system which comprises:
a therapeutically effective amount of an antiemetic; at least one dermal penetration
enhancer, which is a safe skin-tolerant ester sunscreen ester; and at least one
volatile liquid. The invention also provides a method for administering at least
one systemic acting antiemetic thereof to an animal which comprises applying an
effective amount of the antiemetic in the form of the drug delivery system of the
present invention.