Inhibitors of phospholipase enzymes

   
   

Novel compounds are disclosed which inhibit the activity of phospholipase enzymes in a mammal, particularly cytosolic phospholipase A2. Pharmaceutical compositions comprising such compounds and methods of treatment using such compositions are also disclosed.

 
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> Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade

> Process for the preparation of 1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta [B] [1,4] diazepino- [6,7,1-hi] indole derivatives

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