Fluorescent sensor compounds having the formula:
##STR1##
- wherein L is selected from the group consisting of alkyl, alkylene,
aryl, cycloalkyl, alkoxy, aryloxy, arylalkyl, and arylalkyloxyl;
- each m, m, n, n, p, and p is independently an
integer from 0 to 4, inclusive; and
- each R1, R1, R2, R2,
R3 and R3 is independently selected from the group
consisting of hydrogen, alkyl, alkylene, aryl, cycloalkyl, alkoxy, aryloxy, arylalkyl,
arylalkyloxyl, halo, substituted and unsubstituted amino, and substituted and unsubstituted
thiol, are useful for the selective detection of saccharides such as glucose and
sialyl Lewis X. The compounds find particular use in detecting saccharides in biological
samples, and in detecting cancer cells that express cell surface polysaccharides
such as sialyl Lewis X.
|
|
|