Disclosed is a method for producing glycine, which comprises subjecting
an aqueous solution of glycinonitrile to a hydrolysis reaction in a hydrolysis
reaction system under the action of a microbial enzyme, thereby converting the
glycinonitrile to glycine while by-producing ammonia, wherein the hydrolysis reaction
system contains at least one organic impurity compound inhibiting the microbial
enzyme, wherein the organic impurity compound has a molecular weight of 95 or more
and contains at least one member selected from the group consisting of a nitrile
group, a carboxyl group, an amide group, an amino group, a hydroxyl group and a
trimethyleneamine structure, and wherein the hydrolysis reaction is performed under
conditions wherein, during the hydrolysis reaction, the content of the organic
impurity compound inhibiting the microbial enzyme in the hydrolysis reaction system
is maintained at a level of 10% by weight or less, based on the weight of the hydrolysis
reaction system.
