Systems and methods provide baroreflex activation to treat or reduce pain
and/or to cause or enhance sedation or sleep. Methods involve activating
the baroreflex system to provide pain reduction, sedation, improved sleep
or some combination thereof. Systems include at least one baroreflex
activation device, at least one sensor for sensing physiological activity
of the patient, and a processor coupled with the baroreflex activation
device(s) and the sensor(s) for processing sensed data received from the
sensor and for activating the baroreflex activation device. In some
embodiments, the system is fully implantable within a patient, such as in
an intravascular, extravascular or intramural location.