Triazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1

   
   

Triazole derivatives of structural formula I are selective inhibitors of the 11.beta.-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other symptoms associated with NIDDM.

 
Web www.patentalert.com

< Methods of using zonisamide as an adjunctive therapy for partial seizures

< Responsive gastric stimulator

> 5-Sulphanyl-4h-1,2,4-triazole derivatives and their use as medicine

> N-alkyl pyrroles as HMG-CoA reductase inhibitors

~ 00194