The present invention provides Orphanin FQ receptor nucleic acid
sequences. Specifically, the present invention provides nucleic acid
sequences of differentially expressed splice variants of the Orphanin FQ
receptor. The present invention also provides methods of using the
Orphanin FQ receptor nucleic acid sequences for the identification of
pharmaceutical agents and the generation of animal models of Orphanin FQ
receptor-mediated disease states. The present invention thus provides
improved method of screening potential therapeutics useful in the
treatment of a variety of disease states mediated by Orphanin FQ
signaling.
