Bradykinin B1 receptor antagonists

   
   

Bradykinin B1-receptor antagonists of formula ##STR1##

are disclosed. The compounds are useful for treating diseases associated with inappropriate bradykinin receptor activity, such as diabetic vasculopathy, inflammation, pain, hyperalgesia, asthma, rhinitis, septic shock, atherosclerosis and multiple sclerosis. Pyrimidines, triazines, and anilines in which Q is imidazolyl or pyrrolyl are particularly preferred.

 
Web www.patentalert.com

< N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives

< FAIMS apparatus and method using carrier gas of mixed composition

> Antipsychotic sulfonamide-heterocycles, and methods of use thereof

> Nucleic acid encoding small conductance calcium-activated potassium channel (SK1)

~ 00195