The invention relates to 1-(R.sup.1)-2-(R.sup.2)-3-(Y-X-NH-A- or
Z-A-)-4,5,6,7-R).sub.0-4-indoles, and their acid addition salts where the
compounds are basic, wherein A is C.sub.1-4 alkylene, X is >CH.sub.2,
>C=O or >C=S, and the other symbols have various defined values,
and to pharmaceutical, skin-protective and cosmetic compositions which
comprise them.