The present invention relates i.a. to nucleic acid sequences encoding novel Lawsonia
intracellularis proteins. It furthermore relates to DNA fragments, recombinant
DNA molecules and live recombinant carriers comprising these sequences. Also it
relates to host cells comprising such nucleic acid sequences, DNA fragments, recombinant
DNA molecules and live recombinant carriers. Moreover, the invention relates to
proteins encoded by these nucleotide sequences. The invention also relates to vaccines
for combating Lawsonia intracellularis infections and methods for the preparation
thereof. Finally the invention relates to diagnostic tests for the detection of
Lawsonia intracellularis DNA, the detection of Lawsonia intracellularis
antigens and of antibodies against Lawsonia intracellularis.