Human chemokine polypeptides and DNA (RNA) encoding such chemokine polypeptides
and a procedure for producing such polypeptides by recombinant techniques is disclosed.
Also disclosed are methods for utilizing such chemokine polypeptides for the treatment
of leukemia, tumors, chronic infections, autoimmune disease, fibrotic disorders,
wound healing and psoriasis. Antagonists against such chemokine polypeptides and
their use as a therapeutic to treat rheumatoid arthritis, autoimmune and chronic
inflammatory and infective diseases, allergic reactions, prostaglandin-independent
fever and bone marrow failure are also disclosed. Diagnostic assays for identifying
mutations in nucleic acid sequence encoding a polypeptide of the present invention
and for detecting altered levels of the polypeptide of the present invention are
also disclosed.
