It is described a process for the synthesis of optically active anthracyclines
by the fact that the key intermediate (R)2-acetyl-2-hydroxy-1,2,3,4-tetrahydronaphtalene
5,8-dialkoxy-3,4-dihydronaphtalene by acylation asymmetric dihydroxylation, transformation
into chloroacetate, dehydrochloridation and final hydrolysis.