A process in which urine is optionally filtered to remove solid extraneous
matter and optionally treated so as to reduce the phenolic content of the
urine to give and the resulting fluid is then subjected to a solid
extraction of the major concentration steroids content therefrom by a
first suitable resin (to yield a first resin laden with major
concentration steroids and a minor concentration steroid laden first
liquid remainder). The minor concentration steroid liquid remainder is
subjected to a solid extraction of the minor concentration steroid
content therefrom by a second suitable resin (to yield a second resin
laden with minor concentration steroids and a second liquid remainder).
The first and second resins laden with their respective steroids are then
eluted and the eluates are collected separately and optionally subjected
to further purification and chromatographic separations, with each
resulting separate collection being analyzed for the steroid content
thereof. The separate analyzed materials are dried and stored for
recombination in an appropriate manner to meet a desired profile. The
ultimate product has very nearly the same steroid components and
concentrations from batch to batch.
