A method for genotyping multiple samples at multiple genetic loci in a single
assay
is provided. Microarrays of genomic segments representing discrete loci are formed
and hybridized with mixtures of synthetic oligonucleotides that are complementary
to the genomic segments. Genotyping information is derived by reading the microarray
signals. The method can be used to characterize samples from diverse biological
sources and for a variety of applications.