The present invention relates to novel methods for stabilizing aqueous
deacylation, via use of buffers in the production of sucralose. The
present invention provides a process for producing sucralose from an
acyl-sucralose compound whereby the acyl-sucralose compound is deacylated
in the presence of a buffering agent, which stabilizes the pH of the feed
mixture and decreases the accumulation of undesired anhydro compounds.
Further, the present invention provides a process whereby the
acyl-sucralose compound is deacylated directly either prior to or after
removal of the tertiary amide reaction vehicle from the neutralized
chlorination feed mixture. An aqueous solution of sucralose including
salts and other compounds is produced, from which sucralose is recovered
by extraction and purified by crystallization.
