The present invention relates to compounds which comprise a 4-substituted
piperidine ring linked to a substituted or unsubstituted hydrocarbyl
ring. The compounds, including all enatiomeric and diasteriomeric forms
and pharmaceutically acceptable salts thereof, have the formula: 1
wherein preferably R is substituted aryl, W is a pendant unit having the
formula:
-L-Q
L is a linking unit, Q is preferably a cyclic hydrocarbyl unit; W.sup.1 is
preferably a carbocyclic unit and W.sup.2 is a heteroatom comprising
unit.