Present invention is a system of blood glucose monitoring and intensive
insulin therapy in a ICU for strict maintenance of normoglycemia which
reduces intensive care and hospital mortality and morbidity of critically
ill adult patients. The findings of present study also reveal factors
determining insulin doses needed to maintain normoglycemia as well as the
impact of insulin dose versus blood glucose level on the observed outcome
benefits have been established. The invention provides a control system
that adapts the flow of the insulin infusion based on insulin requirement
calculated by blood glucose levels and clinical parameters such as
history of diabetes, Body Mass Index, blood glucose level on admission,
reason of ICU admission, time in the ICU, type and severity of illness,
caloric intake, obesity, drugs affecting insulin sensitivity). This
automated insulin monitoring systems significantly reduces the workload
and human resource management problems for intensive insulin therapy in
patients in the ICU.
