Disclosed are a nucleic acid molecule from nematodes encoding for
purine/pyrimidine phosphoribosyl transferase (PPPT) polypeptides. The
PPPT-like polypeptide sequence is also provided, as are vectors, host
cells, and recombinant methods for production of PPPT-like nucleotides
and polypeptides. The invention further relates to screening methods for
identifying inhibitors and/or activators, as well as methods for antibody
production.