HIV protease inhibitors
   
   

The present invention relates to novel dihydropyrones of Formula I ##STR1##

wherein X is NH or NR8, which inhibit the HIV aspartyl protease blocking HIV infectivity. The dihydropyrones are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS.

 
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< Cyclosporin with improved activity profile

< T-cell immunoregulatory molecule

> NF-AT polypeptides and polynucleotides and screening methods for immunosuppressive agents

> Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
~ 00198