A closed loop system uses (a) the intensity of the diaphragm electromyogram (EMG)
for a given inspiratory volume; (b) the inspiratory volume for a given EMG intensity;
or (c) a combination of (a) and (b); in view of controlling the level of gas flow,
gas volume or gas pressure delivered by a mechanical (lung) ventilator. The closed
loop ventilator system enables for automatic or manual adjustment of the level
of inspiratory support in proportion to changes in the neuro-ventilatory efficiency
such that the neural drive remains stable at a desired target level. An alarm can
also be used to detect changes in neuroventilatory efficiency in view of performing
manual adjustments.
