The present invention relates to a process for labeling a synthetic or natural
ribonucleic acid (RNA). It also relates to RNA fragments, which have been labeled
by fragmenting the RNA to free a terminal phosphate of each fragment for further
reaction, and labeling each fragment at the freed terminal phosphate which is located
at the 3 end and/or the 5 end of each fragment of the RNA, and
to the use of such RNA fragments, for example, in the field of medical diagnosis.