A medical device system comprising a guide catheter and a leaflet fastening applicator,
the guide catheter having suitable dimensions for deployment and insertion percutaneously
into a human heart in a vicinity of a heart valve, the leaflet fastening applicator
having a size allowing insertion through the guide catheter and being capable of
holding portions of opposing heart valve leaflets, wherein the fastening applicator
comprises a pair of grasping-electrodes adapted for holding and engaging the portions
of opposing heart valve leaflets together and for applying energy to fasten the
portions, in which valve leaflets can be captured and securely fastened, thereby
improving coaptation of the leaflets and improving competence of the valve.