Disclosed are newborn infant formulas comprising fat, carbohydrate, and
from 0.5 to 2.5 g of protein per 100 ml of formula, wherein the formula
has a caloric density of from 25 to 50 kcal per 100 ml of formula. Also
disclosed are methods of administering the infant formulas to provide
newborns with optimal nutrition, to reduce the occurrence or extent of
insulin resistance in an individual later in life, to reduce the
occurrence or extent of atherosclerosis or coronary artery disease in an
individual later in life, or combinations thereof, by feeding newborn
infants the newborn infant formula described herein.