The invention relates to an isolated nucleic acid of the human FGF-1 gene
having IRES (internal ribosome entry site) activity, said nucleotide
sequence being derived from the 5' non-translated region (5'NTR) end of
the human FGF-1 gene. The invention also concerns an expression cassette
of at least one molecule of interest in a eukaryotic cell comprising at
least one of said sequences. The cassette can be inserted directly or in
the form of a vector in a host cell, hence the invention further relates
to the recombinant vectors and the host cell transfected by said vector
or the cassette.