Disclosed are methods and compositions for the treatment of hyperlipidemia
and conditions associated therewith, such as CHD, ischemic stroke,
restenosis after angioplasty, peripheral vascular disease, intermittent
claudication, myocardial infarction (e.g. necrosis and apoptosis),
dyslipidemia and post-prandial lipemia. The methods include
administration of a therapeutically effective amount of a compound of
formula I 1
wherein
R is substituted adamantyl; and
N is 0 to 3; in free form or in acid addition salt form, and a
pharmaceutically acceptable carrier.