The instant invention relates to the use of compounds that are effective
as selective opiate receptor modulators for the manufacture of
pharmaceuticals for the diagnosis and/or the treatment of disorders, said
disorders being selected from eating disorders and digestive disorders,
especially psychogenic eating disorders, for the manufacture of a
pharmaceutical effective for modulating, the gastrointestinal tonus, and
to pharmaceutical composition, comprising one or more of said modulator
compounds and one or more compounds that are effective as appetite
depressant.