An ankle brace for comfortably supporting an ankle of a wearer by inhibiting motion between a foot and lower leg of the wearer. The ankle brace employs a laminated, moisture-wicking material for leg and foot portions that improves wearability during athletic activities. The leg and foot portions are combined with medial and lateral stays that are supported within pockets of the leg portion so as to provide medial and lateral stability for the ankle. A strapping unit is used to further improve stability with a pair of straps that are formed of the same piece of laminate material as the foot portion and extend upwards from the foot portion to cross over the ankle and attach to the leg portion. Advantageously, constructing the straps from the same piece of material as the foot portion eliminates fasteners and overlapping material and allows the ankle brace to be used with off-the-shelf footwear.