A melanin-concentrating hormone antagonist comprising a compound of the formula
(I):
##STR1##
wherein Ar1 is a cyclic group which may be substituted; X and
Y are the same or different and are a spacer having a main chain of 1 to 6 atoms;
Ar is a condensed polycyclic aromatic ring which may be substituted; R1 and
R2 are the same or different and are hydrogen atom or a hydrocarbon
group which may be substituted; or R1 and R2, together with
the adjacent nitrogen atom, may form a nitrogen-containing heterocyclic ring which
may be substituted; or R2, together with the adjacent nitrogen atom
and Y, may form a nitrogen-containing heterocyclic ring which may be substituted;
or R2, together with the adjacent nitrogen atom, Y and Ar, may form
a condensed ring; or a salt thereof is useful as an agent for preventing or treating
obesity, etc.