A computer peripheral input system with two input types and a method of data communication for the same is provided. The computer peripheral input system comprises a first input module, a second input module and control means having a communication interface installed therein. The first input module is used for inputting at least a first input data and generating a first input signal corresponding thereto. The second input module is used for inputting at least a second input data and generating a second input signal corresponding thereto. Control means reads and processes the first and second input signals, and then stores a first and second information respectively corresponding thereto. The first information represents the first input data. The second information represents the second input data. The communication interface sends the first and second information stored in control means by a polling method.