The object of the present invention is to provide soluble -amyloid precursor
protein secretory stimulators, which are effective in treating neurodegenerative
diseases as well as cerebrovascular disorder-induced neuronopathy. More specifically,
the present invention provides a novel compound of the following Formula (I) or
a salt or prodrug thereof:
##STR1##
[wherein R1 and R2 each represent a hydrogen atom
or a lower alkyl group, etc., Ar1 and the ring B each represent an optionally
substituted aromatic group, the ring A represents an optionally substituted benzene
ring, the ring C represents an optionally substituted 4- to 8-membered ring which
may further be condensed with an optionally substituted ring, X represents CH or
N, and Y represents CH or N].